0.508 • • 0.11 0.07 A21 Desamido • • 27.29 28.65 • • 0.808 0.360 • • 0.10 0.05 Multimer • 46.23 • 2.575 • 0.29 Insulin Human USP Standard Identity Retention Time Peak Area Relative Area % Insulin • 21.06 • 1275.883 • 98.35 A5/B4 Desamido • 23.29 • 3.084 • 0.23 • 25.3

26.3 • 0.508 • 0.07 A21 Desamido • 27.29 • 0.808 • 0.10 • 28.65 • 0.360 • 0.05 Multimer • 46.23 • 2.575 • 0.29 Insulin Human USP Standard Identity Retention Time Peak Area Relative Area % Insulin • 21.06 • 1275.883 • 98.35 A5/B4 Desamido • 23.29 • 3.084 • 25.36 • 0.2