growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release. J. Clin. Invest. 94:1277-1288. Hitzemann, R., Murphy, M., Curell, J. (1985) Opiate receptor thermodynamics: agonist and antogonist binding. Eur. J. Pharmacol. 108:171-177 Hoyer, D.,Pompe, B., Herzel, H., Zwiener,