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on the day before delivery. labor was compli- cated by prolonged rupture of membranes, and delivery was by vacuum extraction for meconium staining. Apgar scores were 2, 3, and 5 at 1, 5, and 10 min, respectively. He had poor respiratory effort and hypotonia and required intubation. Upon transfer to C

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s. The median postdelivery age at the time of study was 7.5 days for the control group and 4 days for the treatment group. All infants had 5-minute Apgar scores of 7 or greater. There were no significant differences between groups for any of these background variables. The parents of all infants were