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M. till, PhD Van uani Ventures, Senior Partner Bernie Krause, PhD MN Sanctuary Inc.. President James
or 1) administration of the grant by The Institute, including distribution of funds for personnel, equipment, and supplies to the two participating NICUs; and 2) ensuring adherence of all investigators to the design and methods of the clinical trials. Dr. Tramo, Principal Investigator, Director of Th
baby's diagnosis, parents anguish, nurture false hope, wrestle with feelings of guilt—and all the while, treatment and counseling are delayed. Now, Saunders et at describe a method that uses whole-genome sequencing (WGS) to achieve a differential diagnosis of genetic disorders in 50 hours rather than the
e genetic diseases (11-13). Although this pro- portion has remained unchanged for the past 20 years, the precise prevalence of monogenic diseases in NICUs is poorly understood be- cause ascertainment rates are low. Serial gene sequencing is too slow to be clinically useful for NICU diagnosis. Newborn s
41(21:483-494. 16. Starr A, Amlic RN, Martin WH, Sanders S. Development of audi- tory function in newborn
routine pro- cedures administered to hospitalized infants have been shown to elicit a stress response:It" A recent study of 430 infants admitted to NICUs in Paris found that on average, each infant received 12 painful procedures daily during their first 2 weeks in the NICU 51 In another study, 54 inf
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