Epstein Secrets

CONFIDENTIAL December , 2012 Mr. Boris Nikolie RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you

CONFIDENTIAL December , 2012 Mr. Boris Nikolie RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen

ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA_R1_00464119 EFTA01977562

ND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA_R1_00464119 EFTA01977562

y of their respective affiliates or existing investment relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due d

"Schrodinger") was held at the above place and time. Mr. Ardai, presiding as Chairman of the meeting, conducted a roll call and confirmed that Mr. Nikolic, Mr. Farid, Mr. Salkind and Mr. Friesner were present, and, finding a quorum had been established, called to order the meeting. Each member of the B

nference BOARD MEMBERS Charles Ardai PRESENT: Boris Nikolic Lou Salkind (by phone) Ramy Farid Richard Frie

nference BOARD MEMBERS Charles Ardai PRESENT: Boris Nikolic Lou Salkind (by phone) Ramy Farid Rich

h certain of the Company's proprietary software. Questions were asked and a full discussion followed. Ms. Tran informed the Board that consent from Cascade Investment, L.L.C. would be required pursuant to the Company's Certificate of Incorporation. 7. Funding Richard Friesner's lab at Columbia University Next,

derstanding Regarding New Investment Entity Dear Larry: This letter sets forth certain general understandings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an Employment Agreement with bgC3. This letter does is not intended to alter the terms of that Employment Agr

dings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an Employm

erstandings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an

y of their respective affiliates or existing investment relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting scientific and operational due diligence as

ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA00585574

CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen

CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Inves

y of their respective affiliates or existing investment relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due d

ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA00585570

CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen

CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Inves

y of their respective affiliates or existing investment relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due d