relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting scientific and operational due diligence as BN determines in his sole discretion to be appropri

relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3

relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3

- Valuation Methodology and IRR Calculation. 12 Yuri Milner and Saurabh Gupta invested their personal capital, Boris Nikolic invested on behalf of Gates Ventures STRICTLY CONFIDENTIAL 19 Commented (Al): Stedmar numbs+ Author EFTA00586875 Sm Date Amount Entry valuation Current valuation Gros IRK

e Pellini; Jason Ryan; McGivern, Arthur R Subject: Foundation-Series B Extension Rodi: To recap the conversation we had a few minutes ago, FMI and Gates Ventures will enter into an agreement in the form attached. This agreement provides GV with information rights that are equivalent to the information rights

relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3

Biosys Capital Partners, LP October_, 2014 Gates Ventures, LLC 2365 Carillon Point Kirkland, WA 98033 Re: Biosys Capital Partners, LP Ladies and Gentlemen: Reference is hereby made to the Agreement of L