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CONFIDENTIAL December , 2012 Mr. Boris Nikolie RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you
CONFIDENTIAL December , 2012 Mr. Boris Nikolie RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen
ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA_R1_00464119 EFTA01977562
ND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA_R1_00464119 EFTA01977562
relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3
valent to the information rights currently provided by FMI to Labcorp and Roche Ventures. Mike Pellini would be happy to discuss directly with you, Boris, John, Allan or others how these rights can effectively be managed to meet GV's expectations. Mike's numbers are as follows: office-617.418.2244 an
cationegmail.comueevacationifpgmail.cornj From: Boris Nikolic Sent Fri 7/5/2013 10:38:34 PM Subject: FW: Fou
egmail.comueevacationifpgmail.cornj From: Boris Nikolic Sent Fri 7/5/2013 10:38:34 PM Subject: FW: Fou
e Pellini; Jason Ryan; McGivern, Arthur R Subject: Foundation-Series B Extension Rodi: To recap the conversation we had a few minutes ago, FMI and Gates Ventures will enter into an agreement in the form attached. This agreement provides GV with information rights that are equivalent to the information rights
derstanding Regarding New Investment Entity Dear Larry: This letter sets forth certain general understandings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an Employment Agreement with bgC3. This letter does is not intended to alter the terms of that Employment Agr
dings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an Employm
erstandings by and between bgC3 LLC ("bgC3") and Boris Nikolic ("BN"). BN has previously entered into an
relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting scientific and operational due diligence as BN determines in his sole discretion to be appropri
ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA00585574
CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen
CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Inves
relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3
ward to working with you. Sincerely, bgC3 LLC By: Larry Cohen, Manager — Business Operations AGREED AND ACCEPTED TO THIS day of December, 2012 Boris Nikolic - 4 - EFTA00585570
CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Investment Entity Dear Boris: This letter sets forth certain general understandings by and between you ("BN") and bgC3 LLC ("bgC3"). BN has previously entered into an Employmen
CONFIDENTIAL December , 2012 Mr. Boris Nikolic RE: Letter of Understanding Regarding New Inves
relationships (including, without limitation, "BGI," the Bill and Melinda Gates Foundation, Cascade Investment, L.L.C., Intellectual Ventures LLC, Gates Ventures, LLC, and Microsoft Corporation); and • Conducting appropriate scientific and operational due diligence on all Opportunities. Activities of bgC3
1990 and 1992 and subsequently joined the World Bank where he was involved in the development of the financial sector in Russia. Boris Nlkolk Dr. Boris Nikolic is a Chief Advisor for Science and Technology to Bill Gates at Bill Gates Catalyst 3 (bgc3), Bill Gates Ventures (BGV) and at the Bill & Melinda Gat
Science and Technology to Bill Gates at Bill Gates Catalyst 3 (bgc3), Bill Gates Ventures (BGV) and at the Bill & Melinda Gates Foundation (BMGF). Boris has led investment activities at these Gates-affiliated organizations on both the for-profit and non-for-profit aspects of Bill Gates' activities.
ceived his MD from Zagreb Medical School and his clinical training from the University's Medical Center, University of Zagreb, Croatia. In 1994, Dr. Nikolic joined the Harvard Graduate Program in Immunology. Subsequently, Boris continued to serve in roles of increasing authority including postdoctoral f
- Valuation Methodology and IRR Calculation. 12 Yuri Milner and Saurabh Gupta invested their personal capital, Boris Nikolic invested on behalf of Gates Ventures STRICTLY CONFIDENTIAL 19 Commented (Al): Stedmar numbs+ Author EFTA00586875 Sm Date Amount Entry valuation Current valuation Gros IRK
Entities connected to both Boris Nikolic and Gates Ventures

Robert Gates
PERSON
Bill Gates
PERSON
Michael Cohen
PERSON
Melinda Gates
PERSON
Larry Cohen
PERSON
Bill & Melinda Gates Foundation
ORGANIZATIONthe State of Washington
LOCATIONCascade Investment
ORGANIZATIONOpportunities
ORGANIZATIONEmployment Agreement
ORGANIZATIONBusiness Operations
ORGANIZATIONIntellectual Ventures LLC
ORGANIZATION
Principals
ORGANIZATION