Epstein Secrets

of tumor suppressor gene inactivation. P Natl Acad Sci USA 101: 10635-10638. Page 2 of 16 EFTA_R1_01519426 EFTA02443860 46. Nowak MA, A Sasaki, C Taylor, D Fudenberg (2004). Emergence of cooperation and evolutionary stability in finite populations. Nature 428: 646-650. 47. Nowak MA, K Sigmund (2004)

W Brook, R Frankham (2004). Most species are not driven to extinction before genetic factors impact them. P Natl Acad Sci USA 101: 15261-15264. 55. Taylor C, D Fudenberg, A Sasaki, MA Nowak (2004). Evolutionary game dynamics in finite populations. B Math Biol 66: 1621-1644. 56. Turelli M, NH Barton (200

15: 461-467. Gilligan DM, DA Briscoe, R Frankham (2005). Comparative losses of quantitative and molecular genetic variation in finite populations of Drosophila melanogaster. Genet Res 85: 47-55. 68. Gilligan DM, DA Briscoe, R Frankham (2005). Comparative losses of quantitative and molecular genetic variat

game dynamics of infinite populations. The replicator equation, in which general payoffs are inter- preted as contributions to individual fitness (Taylor and Jonker, 1978; Hofbauer et al., 1979; Zeeman, 1980; Schuster and Sigmund, 1983; Hofbauer and Sigmund, 1988, 1998) provides an evolution- ary set

tion Games and Evolutionary Dynamics. MIT Press. Cambridge. Massachusetts. Sandler. L. Hiraizumi. Y.. 1960. Meiotic drive in natural populations of Drosophila melanogaster. V. On the nature of the SD region. Genetics 45. 1617-1689. Sandler. L. Novitsky, E.. 1957. Meiotic drive as an evolutionary force. Am

ie, M. Ruffier.M.Schuster, D Sabra/ Y. A. Tang K Taylor, S. Trevanien, J. Vandrevcova, S. White, M. Wils

ignal, which is essential for p•catenin to perform transcriptional regulatory functions in the nucleus (61). BCL9L is one of two human homologs of Drosophila legless (Igs), a segment polarity gene required for Wnt signaling during develop- ment lgs-deficient flies die as pharate adults with Wnt-related de

tions above, we make the substitution p= I -q-r. Then the 164 (autonomous) system above is described by dq = fq(q,r) dr dt =fr(q,r). • 165 We Taylor expand to linearize the system near a given fixed point (q• ,r ) and consider the 166 Jacobian, given by raqa (qtr.) I aq j(qtrt) = afr l (qtr.

systems for insect disease vectors. Nat. Rev. Genet 217 7, 427-435 (2006). 218 14. Charlesworth, B. & Langley, C. H. The population genetics of Drosophila transposable 219 elements. Amt. Rev. Genet. 23,251-287 (1989). 220 15. Chen, C.-H. et at. A Synthetic Maternal-Effect Selfish Genetic Element Dr