Document Mentions (3 shared documents)

EFTA00665629

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urons connect up in specific ways: http://www.sc iencedirect.corn/science/article/pii/50092867404007962 Best, Ed On Sat, Jul 8, 2017 at 5:55 PM, Joichi Ito <[email protected]> wrote: Nice. So do we understand how the genomes encodes these things? Is there a common language genetically? - Joi (Tip: Use NRR to mean No Re

From: "Ed Boyden, To: Joichi Ito [email protected]> Cc: Jeffrey Epstein jeevacat

dance of neurons in very specific patterns. Some neurons also bear, on their surfaces, receptors that talk to receptors on other cells. For example, Drosophila splice one gene into 30,000 kinds, which then help neurons connect up in specific ways: http://www.sc iencedirect.corn/science/article/pii/50092867

EFTA02367540

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From: Ed Boyden, Sent: Monday, July 10, 2017 3:54 PM To: Joichi Ito Cc: , Jeffrey Epstein; Nowak, Martin Subject: Re: Very interesting! In the brain t=ere are countless "handshakes" -- one cell releases a messenger,

rticle/pi4S0092867404007962 <http://www.sciencedirect.com/science/art=cle/pii/S0092867404007962> Best, Ed </=iv> On Sat, Jul 8= 2017 at 5:55 PM, Joichi Ito < <mailt » wrote: =blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:lp= flccc solid;padding-left:lex"> Nice. So do we understan

Sent: Monday, July 10, 2017 3:54 PM To: Joichi Ito Cc: , Jeffrey Epstein; Nowak, Martin Subject:

dance of neurons in very specific=patterns. Some neurons also bear, on their surfaces, receptors that =alk to receptors on other cells. For example, Drosophila splice one =ene into 30,000 kinds, which then help neurons connect up in specific ways= http://www.sciencedirect.com/science/article/pi4S0092867404

EFTA00315100

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i• College of Medical Genetics (ACMG) categories Ito 31 (Table 1). This 2 set of variants was evaluat

ignal, which is essential for p•catenin to perform transcriptional regulatory functions in the nucleus (61). BCL9L is one of two human homologs of Drosophila legless (Igs), a segment polarity gene required for Wnt signaling during develop- ment lgs-deficient flies die as pharate adults with Wnt-related de