Epstein Secrets

HENKIN,EDWARD R POKLEPOVIC,DR JERRY MARINO,VERA GRETCHYN PALM BEACH ORTHODOX SYNAGOGU

HEEREN,CRISTINA SCARPA,JOHN F COOLEY,WILLIAM O TRUMP,IVANA WAGNER,JOE

ve each of the family member's genomes sequenced. The genome tests gave Ivana and Antonia the bad news about calpainopathy. Their younger brother, Mario, is free of the disease. Scientists classify calpainopathy, or "calpain," as a limb-girdle muscular dystrophy Type 2a, caused by a mutation in the

cent of human DNA that is translated into exons, the sequences that are used as templates for protein construction. The reason to do both, explains Conley, is that cancer cells, even within a single tumor, often have a hodgepodge of mutations. Re-doing whole exome sequencing dozens of times captures

ject. In the few months since the project began, Con- ley’s team have already found about 100 exception- al

have each of the family member’s genomes sequenced. The genome tests gave Ivana and Antonia the bad news about calpainopathy. Their younger brother, Mario, is free of the disease. Scientists classify calpainopathy, or “calpain,” as a limb-girdle muscular dystrophy Type 2a, caused by a mutation in the g