5/2011 Warne et al. 2012/0165507 Al 6/2012 Jazayeri-Dezfuly et al. (75) Inventors: Shugnang Zhang, Lexington, MA (US); FOREIGN PATENT DOCUMENTS Alexander Rich, Cambridge, MA (US); Karol na Corin. Irvine, CA (US); Lotto EP 1270724 A2 • 2/2003 Cl2N 15/12 T.1Cgler. Linkoping (SE) WO WO 2007/089899 •

rs and consultants for -100 entities. K Generated over $100 billion biotech business worIgivyyMarmyy. Confidential and Proprietary EFTA00586599 Alexander Rich, M.D. Discover of structures of collagen, RNA double helix, tRNA, Z-DNA Academic Biography K Institutions: The William Thompson Sedgwick Profes