20 Phase 2b Trial (Sickle Cell Anemia) 1° Data H2-2019 Phase lb Trial Initiate Trial H2-2020 Phase 2/3 Trial April2017 18 EFTA00292537 Angiocrine Bioscie C\ ANR9q1,111c nce Investment Thesis 1. Prior to value inflection points • Transition to clinical stage • Two clinical assets • Expanding pipe