eft than in the right hemisphere (more than two-fold) in human foetal 14-week-old brains (Sun et al., 2005). In human embryonic 10-week-old brains Reelin is also more highly expressed in the left than in the right hemisphere (about 1.6-fold) (t Sun, unpublished data). Although a larger sample size i

profile, these studies suggest that at least Reelin and MAPT may participate in the process of estab- lishing normal brain laterality. Mutations of Reelin and MAP7'may disrupt normal asymmetry and con- tribute to the pathology of FTD and schizophrenia. It is yet to be understood why FTD patients with

unpublished data). Although a larger sample size is required to draw a comprehensive gene expres- sion profile, these studies suggest that at least Reelin and MAPT may participate in the process of estab- lishing normal brain laterality. Mutations of Reelin and MAP7'may disrupt normal asymmetry and co