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hah ND. Krumholz HM. Ross JS. Clinical trial evi- dence supporting FDA approval of novel therapeutic agents. 2005.2012. JAMA 2014; 311:363.77. 4. Avom J. Approval of a tuberculosis drug based on a paradoxical surrogate measure. JAMA 2013:309:1349-50. 5. Dhruva SS. Bero LA. Redberg RF. Strength of study evid
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