on had no evidence of HSV-I in the gastrointestinal tract (presumably cleared by the immune sys- tem), whereas those that died within the first week p.i. had widespread HSV-1 infection in the enteric nervous system of the esophagus. stomach, and proximal small intestine, as de- tected by immunohistoc

curvature ante stomach), infected penetrating nerves are apparent in the mesenteric attachment of the ShIlitath and proximal duodenum. (0) At 8 days p.i. with IISV.1 strain 17 r. the esophagus of a SOD mouse has widespread viral infection in mycnteric ganglia and interconnecting fibers. Also shown are