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ccharomyces cerevisiae using CRISPR-Cas 240 systems. Nucleic Acids Res. 41, 4336-43 (2013). 241 25. Griffiths A. J. F. An Introduction to enetic Anal wis. . H. Freeman 2005). at 242 243 26. Burt, A. & Koufopanou, V. Homing endonuclease genes: the rise and fall and rise again of 244 a selfish ele
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