ing murder mystery as the authors track down some of the culprits responsible for the intracellular detection of Gram-negative lipopolysaccharides. Kayagaki N, Wong MT, Stowe IB, et al. Science 2013 Sep; 341:1246-9 <http://webr.emv2.com/faculty1000/F1000_Monthly_images/spacer.gif> Mini brains created in