t Kansas City. M069103. USA °School of Medicine. University of Missoun-Kansas Cny. Kansas City. MO 6410& USA. sUni.ersity of Kansas Medical Center. KansisCny. KS66160, USA'1Ilumina Inc,Chesterfad Research Park Little Chesterford. CBIO I XL Essex UK 'These authors contributed equally to this work tic, wh