ere novel in the CMH database and dbSNP disclosed a frame-shifting insertion in the BRCA)-associated protein required for ATM activation-I (BRAT), Chr 7:2,583,573.2,583,574insATCITCTC,c453_454insATCITCTC, . A literature search yielded a very recent study of BRAT) mutations in two infants with lethal, multifocal seizures, hyper- t