es Al. 2001. IL-113 sensitizes intervertebral disc annulus cells to fluid- induced shear stress. J Cell Biochem 82:290-8. Freemont Al. Peakcock TE, Goupille P. Hoyland IA, O'Brien I, Jayson MIV. 1997. Nerve ingrowth into the diseased intervenebral disc in chronic back pain. Lancet 350:178-81. Freemont Al, Watkins A,