reatment. • Recurrence and Metastasis: Develop cancer drugs to prevent recurrence and treat metastasis. Confidential, October 2011 EFTA00317069 The Distribution of Colorectal Cancer Sporadic Rare syndromes \ (70-80%) (<0.1%) / Familial adenomatous Polyposis (FAP) (H%) Hereditary nonpolyposis colorectal cancer (HNPCC)

reatment. • Recurrence and Metastasis: Develop cancer drugs to prevent recurrence and treat metastasis. Confidential, October 2011 EFTA00614053 The Distribution of Colorectal Cancer Sporadic Rare syndromes \ (70-80%) (<0.1%) / Familial adenomatous Polyposis (FAP) (H%) Hereditary nonpolyposis colorectal cancer (HNPCC)