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in large sexual populations with linear chromatomes. Genetics 196: 1167-1183. 43. Ohs? S 0970) Evolution by gene duplication. Springer•Verlag. 44 Jacob F (1977) Evolution and tinkering. Science 196: 1161-1166. 45. 'lama I). Ihnazet•LatiT1011)1be evolutionary origin of orphan genes. Nat Rev Genet 11:6
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