62. Brooks. B. & Karplus, M. Normal modes for specific motions of macromolecules: application to the hinge-bending mode of lysozyme. Proceedings of the National Academy of Sciences 82.4995-4999 (1985). 63. Teeter. M. M. & Case, D. A. Harmonic and quasiharmonic descriptions of crambin. Journal of Physical Chemistry94. 8091-8097 (1990). 64.