CONFIDENTIAL MEMORANDUM TO: Schrodinger, Inc. Board of Directors FROM: Yvonne Tran, Vice President and General Counsel DATE: May 15, 2014 RE: Meeting of Schrodinger, Inc. Board of Directors Monday, May 19, 2014, 2 PM EDT WebEx

one) Ramy Farid Richard Friesner BOARD MEMBERS None ABSENT: OTHERS PRESENT: Rodi Guidero (by phone) Gregg Griner (by phone) Murco Ringnalda Yvonne Tran Cony (by phone) 1. Call to Order. A meeting of the Board of Directors of Schrodinger, Inc. (the "Board"), a Delaware corporation, (the "Company

by accepts the resignation of Mr. Ringnalda as the Secretary of the Company as of the close of business on May 19, 2014; and RESOLVED FURTHER, that Yvonne Tran be, and she hereby is, elected as Secretary of the Company effective immediately, to serve at the discretion of the Board. 4. General Authority

tach_2 JA_&_R_License_and_Software_Dey_Agreement).pdf; Attach_3_(Financial_Statements,_Ql_FY_2013).pdf; Attach_4_(Financial_Presentation).pdf From: Yvonne Tran [mailto: Sent: Thursday, May 15, 2014 6:34 PM To: Ardai, Charles; Richard Friesner; Salkind, Lou; Boris Nikolic; Ramy Farid Cc: Rodi Guidero; Chri