ng that the Dscrl copy number influences growth and vascularization, modulating angiogenesis within the host tumour microenvironment." Lin Chen of the Structural Biology Faculty, explores the therapeutic implications of this finding, observing, "...the fact that DYRK1A, another chromosome 21 gene with tumor suppressor functi

s. However, in this recent 'Must Read' article highlighted on Faculty of 1000 the authors identify an additional catalytic role. Moosa Mohammadi of the Structural Biology Faculty, with Andrew Beenken, explains "They show that the MAPK Fus3 is recruited to the Ste5-bound mitogen-activated protein kinase kinase (MAPICIC) Ste7,