e safety profile (less neurotoxicity than docetaxel and unlike taxanes and vinca alkaloids -no neutropenia or myelosuppression)4 MICROTUBULE veru Chen J el al. J Med Chem 55:7285-7289 2012 I1 Li CM el CI. MOM, Res 29:3053-3043 2012 I Le Y el all Abed Chem 57:73553364 2014 I'28 day ral and dog lox ily :ladi