minute I hear something. On Jan 16, 2018, at 10:38 AM, Kaw, Kristine wrote: Good morning. Just following up regarding Mr. Epstein's decision on how to proceed. I believe the nurse is scheduled to come in this week for teaching and ideally it would be great if she can teach and observe his first medication administration. Please let me know so I can prescribe accordingly. KK From: Sent: Thursday, January 11, 2018 6:10 PM To: Kaw, Kristine Subject: Re: [EXTERNAL] Injectable medication Hi Kristine. Thank you for this! I actually sent Jeffrey a note about this earlier but still ha c not heard back from him. He is been in constant meetings himself. I will ask him again however and use your much more EFTA_R1_01014953 EFTA02242003

well versed paragraph tomorrow morning early! Hope to have an answer soon. Thanks and have a great evening. Sent from my iPhone On Jan 11, 2018, at 6:03 PM, Kaw, Kristine wrote: Sorry for the late respons e. Just finished with patient s. Looking a labs sent from early this month, Lipids done was calculat ed as oppose d to direct LDL. Insuran ce compan ies look for the EFTA_R1_01014954 EFTA02242004

direct LDL when approvi ng medica tions becaus e this is a more accurat e count, therefo re, represe nting a more accurat e cardiov ascular risk equival ent. When the triglyce rides is high, such as in the case of Mr. Epstein, the lab cannot provide an accurat e LDL count. As you can see there was no LDL value given EFTA_R1_01014955 EFTA02242005

-If you want to procee d with insuran ce approv al, he will need to re-take labs with direct LDL. He cannot start Repath a prior to recheck ing labs becaus e it will not be an accurat e reflecti on of his baselin e without medica tions. -If he wants to self pay, Century Specialt y Pharma willing EFTA_R1_01014956 EFTA02242006

to give him a 10% discoun t if e purchas es minimu m of 6 months . They will ship the medica tion over as soon as it's ordered and have it virtuall y the next day. -Here is the breakd own of cost: For the once a month injectio n $1,250/ month with 10% discoun t if he buys minimu m of 6 months For the twice a EFTA_R1_01014957 EFTA02242007

month injectio n $1,150/ month with 10% discoun t if he buys minimu m of 6 months Hope that answer s all your questio ns. I will be availabl e tomorr ow if you have any questio ns. Please let me know what his decisio n is prescri ption to the pharma cy is pendin g his ok. Thanks EFTA_R1_01014958 EFTA02242008