From: "Tramo, Mark Jude" To: "[email protected]" <[email protected]> Subject: attachments Date: Thu, 28 May 2009 03:21:09 +0000 Attachments: 11C-FLBamphetamine09SynapseOPT.pdf; DAligandfteview06CurrMedicinalChem.pdf; 18FfallyprideNoveltySeeking08JNSciOPT.pdf; 18FfallyprideTLE.06EpilepsiaOPT.pdf; 11CcarfentanilPain05JNSciOPT.pdf FYI - some reading related to your insightful questions about ligand-binding PET...the one most relevant to our discussion about dopamine (DA) is the one on amphetamine-evoked changes in cortical D2-receptor labeling with 11C-FLB. (Unfortunately, they didn't obtain magnitude estimates of euphoria in combination with PET, but previous studies have documented the correlation between amphetamine injeciton and 'pleasure' responses.)...the novelty-seeking study is provocative re: DA and creativity... Rasta manana... EFTA00775253