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This FIRST AMENDMENT OF LETTER OF AGREEMENT REGARDING PURCHASE OF PARTNERSHIP INTEREST effective September 3, 2013 by and between William H. Gates ("Gates") and Dr. Boris Nikolic ("Dr. Nikolic") is made on and dated as of October 6.2015 ("Amendment"). WHEREAS, Gates and Dr. Nikolic entered into a cert
uring the first two years of the Payment Period (as defined in the Letter Agreement) to exercise his rights under the Letter Agreement to deliver to Gates Investment Entity Payment Demands (as defined in the Letter Agreement) with respect to the securities of FMI; and WHEREAS, Dr. Nikolic is no longer an observer member attend
his FIRST AMENDMENT OF LETTER OF AGREEMENT REGARDING PURCHASE OF PARTNERSHIP INTEREST effective September 3, 2013 by and between William H. Gates ("Gates") and Dr. Boris Nikolic ("Dr. Nikolic") is made on and dated as of October 6, 2015 ("Amendment"). WHEREAS, Gates and Dr. Nikolic entered into a cer
uring the first two years of the Payment Period (as defined in the Letter Agreement) to exercise his rights under the Letter Agreement to deliver to Gates Investment Entity Payment Demands (as defined in the Letter Agreement) with respect to the securities of FMI; and WHEREAS, Dr. Nikolic is no longer a member of FMI's Board o
his FIRST AMENDMENT OF LETTER OF AGREEMENT REGARDING PURCHASE OF PARTNERSHIP INTEREST effective September 3, 2013 by and between William H. Gates ("Gates") and Dr. Boris Nikolic ("Dr. Nikolic") is made on and dated as of October 6, 2015 ("Amendment"). WHEREAS, Gates and Dr. Nikolic entered into a cer
uring the first two years of the Payment Period (as defined in the Letter Agreement) to exercise his rights under the Letter Agreement to deliver to Gates Investment Entity Payment Demands (as defined in the Letter Agreement) with respect to the securities of FMI; and WHEREAS, Dr. Nikolic is no longer a member of FMI's Board o
his FIRST AMENDMENT OF LETTER OF AGREEMENT REGARDING PURCHASE OF PARTNERSHIP INTEREST effective September 3, 2013 by and between William H. Gates ("Gates") and Dr. Boris Nikolic ("Dr. Nikolic") is made on and dated as of October 6, 2015 ("Amendment"). WHEREAS, Gates and Dr. Nikolic entered into a cer
uring the first two years of the Payment Period (as defined in the Letter Agreement) to exercise his rights under the Letter Agreement to deliver to Gates Investment Entity Payment Demands (as defined in the Letter Agreement) with respect to the securities of FMI; and WHEREAS, Dr. Nikolic is no longer a member of FMI's Board o
Entities connected to both Robert Gates and Gates Investment Entity Payment

Bill Gates
PERSON
Boris Nikolic
PERSONthe State of Washington
LOCATIONInvestment Entity Payment Demands
ORGANIZATIONthe ResearchGate Investment
ORGANIZATIONthe Foundation Medicine Investment
ORGANIZATIONthe Board of Directors of Foundation Medicine
ORGANIZATION