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1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
upon your written acceptance of this appointment. Very truly yours, lead- ) Matilda Nieri mn cc: Dr. and Mrs. Alejandro Zaffaroni ACCEPTANCF OF SUCCFSSOR TRUSTEE I accept the nomination of Matilda Nieri and.agree to serve as successor Trustee of the Irrevocable Trust Agreement 4/15/89 for the benefit
1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
upon your written acceptance of this appointment. Very truly yours, lead- ) Matilda Nieri mn cc: Dr. and Mrs. Alejandro Zaffaroni ACCEPTANCF OF SUCCFSSOR TRUSTEE I accept the nomination of Matilda Nieri and.agree to serve as successor Trustee of the Irrevocable Trust Agreement 4/15/89 for the benefit
1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
upon your written acceptance of this appointment. Very truly yours, lead- ) Matilda Nieri mn cc: Dr. and Mrs. Alejandro Zaffaroni ACCEPTANCF OF SUCCFSSOR TRUSTEE I accept the nomination of Matilda Nieri and.agree to serve as successor Trustee of the Irrevocable Trust Agreement 4/15/89 for the benefit
Entities connected to both Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement and SUCCFSSOR

Eric Holder
PERSONRedwood City
LOCATIONthe State of California
LOCATIONThis Trust Agreement
ORGANIZATIONAna Leech
PERSONBrandy Rock Way
LOCATIONMa Leech
PERSONELISA ZAFFARONI
PERSONMartin Gerstel
PERSONJean Wirth's
PERSONLYDA ZAFFARONI
PERSONshari hPeAtc
PERSONRobert C. Mee
PERSONMatilda Nieri
ORGANIZATIONTrustors
ORGANIZATIONthe California Uniform Transfers to Minors
ORGANIZATIONTrusteeship
ORGANIZATIONAffymax N.V.
ORGANIZATIONGigapico, Inc.
ORGANIZATION