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062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 1989 with me until you resign or until you are otherwise unable to act. Said appointment shall be effecti
Entities connected to both ELISA ZAFFARONI and Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement

Eric Holder
PERSONRedwood City
LOCATIONthe State of California
LOCATIONThis Trust Agreement
ORGANIZATIONAna Leech
PERSONBrandy Rock Way
LOCATIONMa Leech
PERSONMartin Gerstel
PERSONJean Wirth's
PERSONLYDA ZAFFARONI
PERSONshari hPeAtc
PERSONRobert C. Mee
PERSONMatilda Nieri
ORGANIZATIONSUCCFSSOR
ORGANIZATIONTrustors
ORGANIZATIONthe California Uniform Transfers to Minors
ORGANIZATIONTrusteeship
ORGANIZATIONAffymax N.V.
ORGANIZATIONGigapico, Inc.
ORGANIZATION