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to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
062 November 8, 1996 Mrs. Ma Leech 3701 Brandy Rock Way Redwood City, CA 94061 RE: IRREVOCABLE TRUST AGREEMENT UTD 04/15/89 FOR THE BENEFIT OF ELISA ZAFFARONI. This Trust Agreement ("the Trust") was executed by Dr. and Mrs. Alejandro C. Zaffaroni as Trustors. and by Matilda Nieri and Martin Gerstel as Tr
Entities connected to both Ana Leech and ELISA ZAFFARONI

Eric Holder
PERSONRedwood City
LOCATIONthe State of California
LOCATIONThis Trust Agreement
ORGANIZATIONBrandy Rock Way
LOCATIONMa Leech
PERSONMartin Gerstel
PERSONJean Wirth's
PERSONLYDA ZAFFARONI
PERSONshari hPeAtc
PERSONRobert C. Mee
PERSONMatilda Nieri
ORGANIZATIONTrustee of the Elsa Zaffaroni Irrevocable Trust Agreement
ORGANIZATIONSUCCFSSOR
ORGANIZATIONTrustors
ORGANIZATIONthe California Uniform Transfers to Minors
ORGANIZATIONTrusteeship
ORGANIZATIONAffymax N.V.
ORGANIZATIONGigapico, Inc.
ORGANIZATION