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. IN WITNESS WHEREOF, the Trustors and Trustees have executed this Trust Agreement this day of-T)critIml:Hr.7 , 1989, effective April 15, 1989. This Trust Agreement is sometimes referred to as being dated April 15, 1989. ALEJANDRO ZAFFARONI 7/e LYDA ZAFFAROWI Trustors. MARTIN 0ERZTEL'.. Trustees. 14. EFTA
to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
. IN WITNESS WHEREOF, the Trustors and Trustees have executed this Trust Agreement this day of-T)critIml:Hr.7 , 1989, effective April 15, 1989. This Trust Agreement is sometimes referred to as being dated April 15, 1989. ALEJANDRO ZAFFARONI 7/e LYDA ZAFFAROII Trustors. MARTIN 0ERZTEL'.. Trustees. 14. EFTA
to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
. IN WITNESS WHEREOF, the Trustors and Trustees have executed this Trust Agreement this day of-T)critIml:Hr.7 , 1989, effective April 15, 1989. This Trust Agreement is sometimes referred to as being dated April 15, 1989. ALEJANDRO ZAFFARONI 7/e LYDA ZAFFAROWI Trustors. MARTIN 0ERZTEL'.. Trustees. 14. EFTA
to be Successor Trustee to Martin Gerstel on April 26. 1995. Jean Wirth died on November 8, 1996. Dear Ana: By this letter, I hereby appoint you, Ana Leech, to serve in Jean Wirth's place as successor Trustee of the Elsa Zaffaroni Irrevocable Trust Agreement dated 4/15/89 and executed on December 3, 19
Entities connected to both This Trust Agreement and Ana Leech

Eric Holder
PERSONRedwood City
LOCATIONthe State of California
LOCATIONBrandy Rock Way
LOCATIONMa Leech
PERSONELISA ZAFFARONI
PERSONMartin Gerstel
PERSONJean Wirth's
PERSONLYDA ZAFFARONI
PERSONshari hPeAtc
PERSONRobert C. Mee
PERSONMatilda Nieri
ORGANIZATIONTrustee of the Elsa Zaffaroni Irrevocable Trust Agreement
ORGANIZATIONSUCCFSSOR
ORGANIZATIONTrustors
ORGANIZATIONthe California Uniform Transfers to Minors
ORGANIZATIONTrusteeship
ORGANIZATIONAffymax N.V.
ORGANIZATIONGigapico, Inc.
ORGANIZATION